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FRIDAY, Aug. 7, 2020 (HealthDay News)<\/p>\n
Whether a frozen or fresh embryo is transferred during fertility<\/a> treatments, the odds of pregnancy<\/a> are roughly the same, according to a new Danish study involving nearly 500 women.<\/p>\n Fresh embryo transfer, however, should still be the gold standard in assisted reproduction for women, the research team said.<\/p>\n There was one exception to that rule, however: Women who are at risk of ovarian hyperstimulation syndrome — a painful response to the use of excess hormones in fertility<\/a> treatments.<\/p>\n Using only frozen embryos (a “freeze-all” strategy) during procedures such as in vitro fertilization<\/a> (IVF<\/a>) has become more common, noted researchers led by Sacha Stormlund, of the fertility clinic at Hvidovre University Hospital, in Copenhagen.<\/p>\n But the new findings “warrant caution in the indiscriminate application of a freeze-all [transfer] strategy when no apparent risk of ovarian hyperstimulation syndrome is present,” the study authors concluded.<\/p>\n For the study, the researchers randomly selected 460 women aged 18 to 39 to receive either frozen or fresh embryos. They found that the pregnancy<\/a> rates weren’t significantly different between the freeze-all and the fresh transfer groups (27.8% versus 29.6%).<\/p>\n There were also no significant differences in the rate of loss of pregnancy between the groups and none of the women experienced severe ovarian hyperstimulation syndrome.<\/p>\n Also, the complication risks were not different between the groups except for higher average birth weight in the frozen group and a higher risk of prematurity in the fresh transfer group, the researchers found. The time it took to become pregnant<\/a> was longer in the freeze-all group, Stormlund’s group said.<\/p>\n Dr. Nicole Noyes directs Northwell Health’s Fertility Preservation Program in New York City. Reading over the new findings, she said decisions around choosing a fresh or frozen embryo during IVF<\/a> or other fertility procedures are tough, because of factors such as the unreliability of preimplantation genetic testing of embryos.<\/p>\n In her opinion, Noyes said, “I believe fresh [often the first candidate embryo used] transfers produce equivalent outcomes in most patient groups and involve much less perturbation of the natural embryo course.”<\/p>\n In fact, she added, “embryo transfer of fresh embryos remains my number-one go-to in IVF today after 30 years of successfully practicing IVF in the New York City metropolitan area at three of the best clinics.”<\/p>\n The new Danish report was published online Aug. 5 in the BMJ<\/i>.<\/p>\n — E.J. Mundell<\/p>\n ![\"MedicalNews\"](\"https:\/\/images.medicinenet.com\/images\/HealthDay\/healthday.png\")
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